Memory Loss
When patients have concerns about memory loss, forgetfulness, or trouble concentrating they may be reluctant to talk about it for fear the symptoms may mean something more serious. Slowing down cognitively in aging is normal. Healthcare practitioners who initiate conversation about memory with their patients provide a needed service. 78 million baby boomers indicate this should be a frequent conversation!
Calcium in the Nervous System
After the age of 40, there is a diminishing supply of calcium-binding proteins in neurons which help protect against prolonged accumulations of intracellular calcium. Unlike calcium in the bones or teeth which help provided strength and structure, ionic calcium in the nervous system is required for the electrical signals of the nervous system to travel to, from and within the brain.
The depletion of calcium-binding proteins in aging creates a scenario in which neurons are vulnerable to excitotoxicity brought on by excess calcium and can lead to cell death. This mechanism has been identified as a key mechanism in age-related cognitive decline.
Prevagen Professional
Prevagen contains the active ingredient apoaequorin, a calcium-binding protein first discovered in jellyfish. The molecule is a proven suitable replacement for human endogenous calcium-binding proteins.
In pre-clinical studies conducted at the University of Wisconsin-Milwaukee, apoaequorin has proven neuroprotective. In a double-blind, placebo-controlled study utilizing computer assessments over 90 days, Prevagen improved executive function and short-term memory scores by 29% compared to placebo in 100 participants who had memory concerns.
